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標(biāo)簽:Tulathromycin A
聯(lián)系人:高小姐
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化學(xué)性質(zhì):
規(guī)格 | 10mM (in 1mL DMSO) 10mg 50mg |
CAS | 217500-96-4 |
別名 | Tulathromycin;Draxxin;CP 472295 |
化學(xué)名 | 11-((4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-((5-hydroxy-4-methoxy-4,6-dimethyl-5-((propylamino)methyl)tetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one |
分子式 | C41H79N3O12 |
分子量 | 806.08 |
溶解度 | ≥ 24.1 mg/mL in DMSO, ≥ 96.8 mg/mL in EtOH |
儲(chǔ)存條件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
產(chǎn)品描述:
Tulathromycin A is a macrolide antibiotic [1].Antibiotics are a type of antimicrobial used in the treatment and prevention of bacterial infection.
Two highly pathogenic strains of M. bovis were incubated into 145 calves. Four days later, calves with clinical BRD were treated subcutaneously with tulathromycin or saline (2.5 mg/kg). BRD-related withdrawals, peak rectal temperatures, and lung lesion scores were significantly lower for tulathromycin-treated calves [2]. In the treatment of cattle at high risk of developing bovine respiratory disease, the cure rate treated with tulathromycin (78%) and tilmicosin (65%) was significantly higher than that treated with saline (23.8%). The cure rate treated with tulathromycin (78.4%) was also significantly higher than tilmicosin (64.9%) [3].
The lowest tulathromycin concentrations inhibiting the 90% growth of isolates (MIC90) were 2 μg/ml for Mannheimia (Pasteurella) haemolytica, 1 μg/ml for Pasteurella multocida (bovine), and 2 μg/ml for Pasteurella multocida (porcine) and ranged from 0.5-4 μg/ml for Histophilus somni and from 4-16 μg/ml for Actinobacillus pleuropneumoniae [1]. Tulathromycin has been approved for use in the treatment and prevention of swine and bovine respiratory disease [1].
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原創(chuàng)作者:上海莼試生物技術(shù)有限公司
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普票匯款信息
賬 戶 名:上海生物
開(kāi) 戶 行:中國(guó)銀行山東省分行營(yíng)業(yè)部
賬 號(hào):2169 2341 6278