產(chǎn)品目錄

規(guī)格	100 mg 250 mg 500 mg 1 g
CAS	529-49-7
別名	N/A
化學(xué)名	N/A
分子式	C13H8O5
分子量	244.2
溶解度	DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 20 mg/ml
儲存條件	-20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

Gentisein is a xanthone that has been found in H. annulatum and has diverse biological activities.1,2,3 It scavenges DPPH radicals and inhibits the activity of α-glucosidase in cell-free assays (IC50s = 23.3 and 14.7 μM, respectively).1,2 Gentisein is cytotoxic against K562 chronic multiple leukemia cells, drug-sensitive HL-60 acute promyelocyte leukemia cells, and multidrug-resistant HL-60/DOX cells (IC50s = 102, 90.9, and 88.3 μM, respectively).3

1.Zhong, F.-F., Chen, Y., and Yang, G.-Z.Prenylated xanthones from the bark of Garcinia xanthochymus and their 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activitiesMolecules15(10)7438-7449(2008) 2.Liu, Y., Zou, L., Ma, L., et al.Synthesis and pharmacological activities of xanthone derivatives as α-glucosidase inhibitorsBioorg. Med. Chem.14(16)5683-5690(2006) 3.Biljali, S., Nedialkov, P., Zheleva-Dimitrova, D., et al.Cytotoxic effects and multidrug resistance modulation by five benzophenones and a xanthone Isolated from Hypericum annulatum Moris SUBSP. AnnulatumBiotechnol. Biotechnol. Equip.27(1)3561-3568(2014)

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原創(chuàng)作者：上海莼試生物技術(shù)有限公司

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