產(chǎn)品目錄

規(guī)格	1mg 5mg
CAS	87414-44-6
別名	N/A
化學(xué)名	N/A
分子式	C19H16O7
分子量	356.3
溶解度	Soluble in DMSO
儲存條件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

Butyrolactone II is a butenolide fungal metabolite that has been found in A. terreus.1 It scavenges 2,2-diphenyl-1-picrylhydrazyl and ABTS free radicals (EC50s = 11.5 and 68.5 μM, respectively). It inhibits 5-lipoxygenase (5-LO; IC50 = 21.43 μg/ml) and α-glucosidase (IC50 = 0.126 mM).2,3

|1. Kang, H.-S., and Kim, J.-P. Butenolide derivatives from the fungus Aspergillus terreus and their radical scavenging activity and protective activity against glutamate-induced excitotoxicity. J. Appl. Biol. Chem. 62:43, (2019).|2. Wang, F.-S., Ke, A.-B., Zhu, J.-T., et al. Butyrolactones, inhibitors of 5-lipoxygenase from fungal metabolites. J. Chin. Pharma. Sci. 19(4), 251-255 (2010).|3. Zhang, L.-H., Feng, B.-M., Zhao, Y.-Q., et al. Polyketide butenolide, diphenyl ether, and benzophenone derivatives from the fungus Aspergillus flavipes PJ03-11. Bioorg. Med. Chem. Lett. 26(2), 346-350 (2016).

特別提醒：

1. 本產(chǎn)品僅供科研使用。請勿用于醫(yī)藥、臨床診斷或治療，食品及化妝品等用途。請勿存放于普通住宅區(qū)。

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原創(chuàng)作者：上海莼試生物技術(shù)有限公司

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